Is this a serious question? Vick... by like a fucking mile.
Eddie George was getting old anyway. His stats just went down and he had a toe injury.
Daunte Culpepper was overrated from day one. His inflation of stats was due to Cris Carter and Randy Moss. Sure, he fell off the face of planet, but he wasn't that good to begin with, he was just a one-year wonder. That injury was pretty bad though.
Marshall Faulk got injured, but he still had almost 1600 total yards, so that's out of the question.
Ray Lewis, in my opinion, wasn't affected by the Madden Curse. People make big deal about him not getting an interception and then the injury at the last game of the season, but that's nitpicky.
McNabb got injured, but he's still doing fine now.
Young got benched, deservedly, and turned emo.
Favre... well, he's old and his own antics hurt himself. He's been doing that before the Madden cover... he only finally got traded. Also, he's the first white person to make the cover of Madden. About fucking time... those racists at EA Sports. Brady should have made the cover... then it would be appropriate.
Alexander may have fallen off the face of the earth after the MVP season, but no one... NO ONE.... touches how bad Vick was. He get's injured, never returns to form, flips off fans, then gets caught in the whole dogfighting deal. He's HATED by a great deal of America and he's in prison. He could possibly never have a career in the NFL again. Vick FTMFL.