Man...I was late to the party and never played Battlefield: Bad Company 2, so I've basically been playing the shit out of that for the last month and a half. I've used them while playing Madden too and they work great. I'm single and don't have to worry about how loud the surround sound system is, but if I did, I would be wearing them anytime I was playing a game.
The best part is that they are wireless and not Bluetooth, and have incredible range.