Dr Strange, Blade, and Avengers 4 will be the only successful movies of the ones recently announced. Strange could be a lot of great actors, depending on the age they set for him. If he is younger, I'd love to see him played by whoever plays Sherlock Holmes in Sherlock (too lazy to look it up) or if they go older, he can be played by quite a few very qualified actors.
Blade is a reboot, so it will have some appeal naturally. Avengers will be a hit no matter what.
As for the rest... I just don't see how they can make it big. They aren't main people, they are secondary at best. People know who the Hulk, Iron Man, or Spiderman are just from their appeal even out of the comics. The Iron Fist? Black Panther? I know these guys, but the average person will have no clue.