Only been 28 Pennsylvania born players to make it into the NHL. I believe Massachusetts alone his more players in the NHL currently than that state has put in historically. W/O breaking it down into Pittsburgh and Philly area players here's the best that PA can put on the ice. I am not even going to bother with a Ontarian team as it would be too hard to pick who is best.
Center - Rj Umburger - decent player
Left Wing - Ryan Malone (decent player but really? that's the best LW it's produced)
Right Wing - George Parros (I guess, but PA has only produced 3 RWs in it history)
Defence- Bob Beers & I don't even know, you would think with 28 players, it would be easy but...
Goalie - Mike Richter The only player of any quality. Arguably the best US goalie, no less than top 5 all time US goalie.
http://www.hockey-reference.com/friv/birthplaces.cgi?country=US&province=&state=PA
That's some hockey mecca Pittsburgh has.